Inflammation After Stroke: Mechanisms and Therapeutic Approaches
نویسندگان
چکیده
منابع مشابه
Maladaptive Plasticity for Motor Recovery after Stroke: Mechanisms and Approaches
Many studies in human and animal models have shown that neural plasticity compensates for the loss of motor function after stroke. However, neural plasticity concerning compensatory movement, activated ipsilateral motor projections and competitive interaction after stroke contributes to maladaptive plasticity, which negatively affects motor recovery. Compensatory movement on the less-affected s...
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Ischemic stroke is the most frequent cause of persistent neurologic disability in modern Western societies. Albeit it is still not clear whether inflammation is merely an epiphenomenon or rather has a disease-promoting function, accumulating evidence implicates inflammation in many forms of acute neurodegenerative disorders including ischemia. The immune cell influx during a neuropathological e...
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BACKGROUND AND PURPOSE We previously showed that mild hypothermia protects against experimental stroke, even when cooling was delayed by 2 hours. Protection may be due in part to inhibiting inflammation. To clarify, we examined leukocyte infiltration, microglial activation, and adhesion molecule expression in models of stroke and pure brain inflammation. METHODS Rats underwent 2-hour middle c...
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A better understanding of the neural substrates that underlie motor recovery after stroke has led to the development of innovative rehabilitation strategies and tools that incorporate key elements of motor skill relearning, that is, intensive motor training involving goal-oriented repeated movements. Robotic devices for the upper limb are increasingly used in rehabilitation. Studies have demons...
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ژورنال
عنوان ژورنال: Translational Stroke Research
سال: 2010
ISSN: 1868-4483,1868-601X
DOI: 10.1007/s12975-010-0023-7